Livestock rearing is part and parcel of the mountain livelihood. The Snow Leopard Friendly Livestock Vaccination Program (SLFLVP) is aimed to 1) enhance household income by cutting down livestock losses to due to diseases; and 2) minimize transmission of contagious diseases from livestock to wild ungulates and carnivores, respectively. In return, the participating communities pledge to ensure protection of wildlife in their respective territories through an enforceable tripartite conservation agreement. The high mortality rate of livestock due to diseases i.e. 4-10 animals per year than depredation by snow leopard and other carnivores i.e. 1-2 animals in the snow leopard range in the country ascertained through research studies ([i]SLF, 2012, Nawaz et al. 2016 and Din et al. 2017[ii]) provide base for the initiation of this program. Piloted in one village in Chitral in 2003, now the program is operational in 25 valleys in GB and Chitral District of KP and has helped reduce livestock mortality due to diseases up to 50%. The SLFLVP is an excellent example of public-private partnership and is implemented in collaboration with the community, government Livestock and Wildlife Departments and SLF. A vaccination calendar is developed during the training of the selected community members referred as Ecosystem Health Workers (EHWs) and followed during the implementation of the program. For each spring and fall vaccination campaigns, the vaccines are procured as per vaccination calendar and in consultation with the EHWs and senior officials of the livestock departments. However, there are times, when a certain fatal disease outbreak is reported from the program sites and that necessitates rapid counteractive measures to offset the catastrophic loses of livestock. The sarcoptic mange is one such disease frequently noticed in GB. This disease has effected wildlife populations ranging from wild ungulates ([iii]Dagleish et al. 2007) to carnivores ([iv]Hameed et al. 2016) in the region and reportedly transmitted from livestock. During our recent consultation with the EHWs and officials of the livestock department for the identification and procurement of vaccines for fall vaccination campaign 2017, all the stakeholders reported occurrence of the disease in animals and proposed treating animals for sarcoptic mange in the program sites. Honoring the request, SLF decided to procure prescribed drug for the disease identified that will be handed over to the EHWs to initiate the fall vaccination campaign starting from the second week of October 2017. This is the third campaign against the disease in GB. The last campaign had been launched in fall 2016 having received report from the Wildlife Department of the potential occurrence of the disease in blue sheep in Shimshal valley of Hunza District. [i] Nawaz, M.A., Ud Din, J., and Buzdar, H. (2016a). The Ecosystem Health Program: A tool to promote the coexistence of livestock owners and Snow Leopards. Pp 188-196 in McCarthy, T.M. and Mallon, D.P. (Eds.), Snow Leopards. Elsevier, New York. SLF (2012). Review of Vaccination Program in Chitral. Unpublished report. Din, J., Ali, H., Ali, A., Younus, M., Mehmood, T., Norma-Rashid, Y. and Nawaz, M.A., 2017. Pastoralist-predator interaction at the roof of the world: Conflict dynamics and implications for conservation. Ecology and Society, 22(2). [iii] Dagleish, M.P., Ali, Q., Powell, R.K., Butz, D. and Woodford, M.H., 2007. Fatal Sarcoptes scabiei infection of blue sheep (Pseudois nayaur) in Pakistan. Journal of Wildlife Diseases, 43(3), pp.512-517. [iv] Hameed, K., Angelone-Alasaad, S., Din, J.U., Nawaz, M.A. and Rossi, L., 2016. The threatening but unpredictable Sarcoptes scabiei: first deadly outbreak in the Himalayan lynx, Lynx lynx isabellinus, from Pakistan. Parasites & vectors, 9(1), p.402.